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Wolfgang Knecht Selected Research

Genee-Wiedemann syndrome

2/2022Protein-lipid interactions of human dihydroorotate dehydrogenase and three mutants associated with Miller syndrome.
1/2022Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome.
1/2020Preparation of human dihydroorotate dehydrogenase for interaction studies with lipid bilayers.

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Wolfgang Knecht Research Topics

Disease

6Neoplasms (Cancer)
07/2020 - 01/2008
3Genee-Wiedemann syndrome
02/2022 - 01/2020
3Inflammation (Inflammations)
06/2011 - 06/2007
2Neoplasm Metastasis (Metastasis)
07/2020 - 01/2019
2Glioma (Gliomas)
06/2015 - 06/2010
2Infections
01/2012 - 07/2006
2Edema (Dropsy)
09/2007 - 06/2007
1Severe Acute Respiratory Syndrome
10/2020
1Cardiovascular Diseases (Cardiovascular Disease)
10/2020
1Inborn Genetic Diseases (Disease, Hereditary)
01/2020
1Rheumatoid Arthritis
01/2020
1Multiple Sclerosis
01/2020
1Hypoxia (Hypoxemia)
01/2020
1Hemorrhage
01/2015
1Virus Diseases (Viral Diseases)
01/2012
1Liver Neoplasms (Liver Cancer)
01/2012
1Pancreatitis
06/2011
1Pain (Aches)
06/2011
1Hyperalgesia
09/2007
1Neurogenic Inflammation
09/2007
1Ileitis
06/2007
1Enteritis
06/2007
1Malaria
03/2003

Drug/Important Bio-Agent (IBA)

6EnzymesIBA
01/2022 - 03/2003
5Dihydroorotate DehydrogenaseIBA
02/2022 - 07/2006
4Proteins (Proteins, Gene)FDA Link
02/2022 - 01/2012
3TrypsinIBA
06/2011 - 06/2007
3Pyridinolcarbamate (P23)IBA
06/2011 - 06/2007
2LipidsIBA
02/2022 - 01/2012
2Carbonic Anhydrase IXIBA
07/2020 - 01/2019
2Protein Isoforms (Isoforms)IBA
01/2019 - 06/2011
2Pharmaceutical PreparationsIBA
01/2019 - 05/2009
2thymidine kinase 1IBA
06/2015 - 06/2010
2PAR-2 ReceptorIBA
06/2011 - 06/2007
2Peroxidase (Myeloperoxidase)IBA
06/2011 - 06/2007
2Phosphotransferases (Kinase)IBA
05/2009 - 03/2003
1QuartzIBA
02/2022
1Lipid Bilayers (Lipid Bilayer)IBA
02/2022
1Lipoprotein(a)IBA
10/2020
1Uridine Monophosphate (UMP)IBA
01/2020
1Indicators and Reagents (Reagents)IBA
01/2019
1Factor XIa (Coagulation Factor XIa)IBA
01/2015
1AnticoagulantsIBA
01/2015
1Antiviral Agents (Antivirals)IBA
01/2012
1PF-429242IBA
01/2012
1Biological ProductsIBA
01/2012
1Peptides (Polypeptides)IBA
06/2011
1Serine Proteases (Serine Protease)IBA
06/2011
1melagatranIBA
06/2011
1Trypsin InhibitorsIBA
06/2011
1AmylasesFDA Link
06/2011
1ProdrugsIBA
06/2010
1GemcitabineFDA Link
05/2009
1Capsaicin (Zostrix)FDA Link
09/2007
1Proteinase-Activated ReceptorsIBA
09/2007
1Peptide Hydrolases (Proteases)FDA Link
06/2007
1IsoenzymesIBA
06/2007
1Tryptases (Tryptase)IBA
06/2007
1Cathepsin CIBA
06/2007
1Clostridium difficile tcdA proteinIBA
06/2007
1SR 140333IBA
06/2007
1Phenobarbital (Luminal)FDA Link
06/2007
1pyrimidineIBA
07/2006

Therapy/Procedure

3Therapeutics
06/2011 - 01/2008
1Liver Transplantation
01/2012
1Injections
06/2011